Cape Girardeau Post Office

NOTICE: The Postal Service is an essential government service, and will remain open wherever possible.

320 N Frederick St, Cape Girardeau, MO 63701

Contact Numbers

Phone: 573-335-5501
TTY: 877-889-2457
Toll-Free: 1-800-Ask-USPS® (275-8777)

Retail Hours

Lobby Hours
PO Box Access Available

Monday 24 hours
Tuesday 24 hours
Wednesday 24 hours
Thursday 24 hours
Friday 24 hours
Saturday 24 hours
Sunday 24 hours

Last Collection Times

Monday 12:30pm
Tuesday 12:30pm
Wednesday 12:30pm
Thursday 12:30pm
Friday 12:30pm
Saturday 2:00pm
Sunday Closed

Passport Appointment Hours*

Monday 9:30am - 3:30pm
Tuesday 9:30am - 3:30pm
Wednesday 9:30am - 3:30pm
Thursday 9:30am - 3:30pm
Friday 9:30am - 3:30pm
Saturday Closed
Sunday Closed

Routine processing has resumed. Please see State Department Response to COVID-19 webpage for more information.
  • Visit our Passport FAQ page for a complete overview of what to bring, what you need to know, and how long it will take.
  • You will need two forms of Identification with copies.
  • A passport quality photo. Available at location.
  • The appropriate application form printed and filled out, and the required fee for applying or renewing.
  • You can find up to date costs, information, and forms at the State Departments Travel Site

*An appointment is required to apply for or renew US Passports. Please Call 573-335-3137 or schedule online.

  • Burial Flags
  • Business Line
  • Business Reply Mail Account Balance
  • Business Reply Mail New Permit
  • Duck Stamps
  • General Delivery
  • Money Orders (Domestic)
  • Money Orders (Inquiry)
  • Money Orders (International)
  • Packaged Stamps
  • Passport Acceptance
  • Passport Photo
  • Pickup Accountable Mail
  • Pickup Hold Mail
  • PO Box Online
  • Lot Parking
  • Passport Appointment Hours

Visit our Links Page for Holiday Schedule, Change of Address, Hold Mail/Stop Delivery, PO Box rentals and fees, and Available Jobs.

*Please call to verify information. Is anything incorrect? Let us know here

Nearby Post Offices:

Cape Carrier Annex
475 Kell Farm Dr
2.3 miles away

Cape Girardeau 2
475 Kell Farm Dr
2.3 miles away

Mc Clure
37914 Grapevine Trl
3.8 miles away

Scott City
605 2nd St E
3.8 miles away


*Comments below are not read by postal employees. Please do not post personal information.

*By clicking Submit, you agree to our Privacy Policy & Terms of Use.


Mail is not consistent, he is unpredictable


I would like my mail person to put my package in a bag and tie to my gate please


Garbage. Customer services sucks. Need to change my address can’t do it online bc I do not have a bank account. Waited in line for twenty minutes only to be told they are out of forms and I have to do it online. Asked my mail carrier if I could get a form said they are no longer allowed to carry them. Will never use usps again would rather pay a private company that wants my business. Hope it gets shut down soon and the whole infrastructure of the mail carriers collapses. Of course then we will have all those dropouts wondering the streets. In short F off keep my mail don’t care anymore. Oh this was the second post office I’ve tried to get this changed.


im trying to reach some compane about malden mo about the mail not sending the wrong adress im getting someone mail not mine , it been 2 years and going on 3 years im still getting some one mail , u need get some one who know how much they love there job ,


I’m trying to reach the USPS here in Cape Girardeau. The number given on this web page is no longer in service. Please supply the correct number so that we can communicate with our postal service.


Why is it cape girardeau post office workers, the ones who actually deliver mail, do not pick up mail you have stamped to be mailed, attached to your mailbox, instead they put mail in the box and walk away? This is the only town i have had this problem in. In 27 years of life, this is the only town that i have had this problem in.


I think they want you to put stamped mail inside the box and put up the little red flag so they know it’s there
• Replied to Weldingink

* is not a part of, or affiliated with, the official United States Postal Service (USPS).